CYB5R2

CYB5R2 (Cytochrome B5 Reductase 2) is a Protein Coding gene. Among its related pathways are Metabolism and Amino sugar and nucleotide sugar metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and cytochrome-b5 reductase activity, acting on NAD(P)H. An important paralog of this gene is CYB5R3.

Full Name

Cytochrome B5 Reductase 2

Function

NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity).

Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1).

Biological Process

Bicarbonate transport Source: Reactome
Sterol biosynthetic process Source: UniProtKB-KW

Cellular Location

Endoplasmic reticulum membrane; Nucleus; Membrane

Anti-CYB5R2 antibodies

Mouse Anti-CYB5R2 Recombinant Antibody (V2-186963) (CBMAB-C6699-LY)

Datasheet

SDS

Target: CYB5R2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: V2-186963

Application*: C, WB

Mouse Anti-CYB5R2 Recombinant Antibody (CBXC-2220) (CBMAB-C5441-CQ)

Datasheet

SDS

Target: CYB5R2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXC-2220

Application*: WB, F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)