DDX59

DDX59 (DEAD-Box Helicase 59) is a Protein Coding gene. Diseases associated with DDX59 include Orofaciodigital Syndrome V and Orofaciodigital Syndrome. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is DDX4.
Full Name
DEAD-Box Helicase 59
Cellular Location
Cytoplasm; Nucleus. Exhibits granular localization in the nucleus, as well as in the cytoplasm.
Involvement in disease
Orofaciodigital syndrome 5 (OFD5):
A form of orofaciodigital syndrome, a group of heterogeneous disorders characterized by malformations of the oral cavity, face and digits, and associated phenotypic abnormalities that lead to the delineation of various subtypes. OFD5 patients show the core features of cleft palate, lobulated tongue, and polydactyly. Additional features include frontal bossing and intellectual disability.
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Anti-DDX59 antibodies

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Target: DDX59
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2G1
Application*: P, WB
Target: DDX59
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F11
Application*: WB
Target: DDX59
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: D0627
Application*: WB, IP, IF, E
Target: DDX59
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: D0623
Application*: WB, IP, IF, E
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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