Mouse Anti-DDX59 Recombinant Antibody (D0623) (V2LY-0425-LY116)

Name: Mouse Anti-DDX59 Recombinant Antibody (D0623)
SKU: V2LY-0425-LY116
Rating: 5 (1 reviews)

See all DDX59 antibodies

Online Inquiry

Datasheet

Summary

Host Animal

Mouse

Specificity

Human, Mouse, Rat

Clone

D0623

Antibody Isotype

IgG1, κ

Application

WB, IP, IF, ELISA

Basic Information

Immunogen

Amino acids 1-22 at the N-terminus of human DDX59.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1, κ

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

Gelatin & PBS

Preservative

Sodium Azide

Concentration

0.2 mg/ml

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

DEAD-Box Helicase 59

Entrez Gene ID

83479

UniProt ID

Q5T1V6

Cellular Location

Cytoplasm; Nucleus. Exhibits granular localization in the nucleus, as well as in the cytoplasm.

Involvement in disease

Orofaciodigital syndrome 5 (OFD5):
A form of orofaciodigital syndrome, a group of heterogeneous disorders characterized by malformations of the oral cavity, face and digits, and associated phenotypic abnormalities that lead to the delineation of various subtypes. OFD5 patients show the core features of cleft palate, lobulated tongue, and polydactyly. Additional features include frontal bossing and intellectual disability.

More Infomation

References

Hu, K. Q., & Ao, X. S. (2022). Long non-coding RNA DLGAP1 antisense RNA 1 accelerates glioma progression via the microRNA-628-5p/DEAD-box helicase 59 pathway. Clinics, 77.

Salpietro, V., Efthymiou, S., Manole, A., Maurya, B., Wiethoff, S., Ashokkumar, B., ... & Houlden, H. (2018). A loss‐of‐function homozygous mutation in DDX59 implicates a conserved DEAD‐box RNA helicase in nervous system development and function. Human mutation, 39(2), 187-192.

Faily, S., Perveen, R., Urquhart, J., Chandler, K., & Clayton-Smith, J. (2017). Confirmation that mutations in DDX59 cause an autosomal recessive form of oral-facial-digital syndrome: Further delineation of the DDX59 phenotype in two new families. European journal of medical genetics, 60(10), 527-532.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-DDX59 Recombinant Antibody (D0623)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-DDX59 Recombinant Antibody (1F11)

Mouse Anti-DDX59 Recombinant Antibody (D0627)

Mouse Anti-DDX59 Recombinant Antibody (2G1)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: