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FMNL1

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]
Full Name
formin-like 1
Function
May play a role in the control of cell motility and survival of macrophages (By similarity).

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.
Biological Process
Actin filament severing Source: UniProtKB
Cell migration Source: GO_Central
Cortical actin cytoskeleton organization Source: UniProtKB
Regulation of cell shape Source: UniProtKB
Cellular Location
Cell membrane; Cytoplasm; Phagosome. Recruited to actin-rich phagosomes during phagocytosis. Translocates to the plasma membrane upon activation by RAC1 (By similarity).
Isoform 3: Cell cortex; Bleb. Colocalized with F-actin in bleb protrusions.
PTM
Myristoylation mediates membrane localization and blebbing.
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Anti-FMNL1 antibodies

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Mouse Anti-FMNL1 Recombinant Antibody (CBXF-3101) (CBMAB-F3797-CQ)

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Target: FMNL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3101
Application*: WB
Datasheet SDS

Mouse Anti-FMNL1 Recombinant Antibody (CBXF-3100) (CBMAB-F3796-CQ)

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Target: FMNL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-3100
Application*: E, WB
Datasheet SDS

Mouse Anti-FMNL1 Recombinant Antibody (CBXF-0770) (CBMAB-F2403-CQ)

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Target: FMNL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0770
Application*: WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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