GATB

GATB (Glutamyl-TRNA Amidotransferase Subunit B) is a protein coding gene. Among its related pathways are tRNA Aminoacylation and Metabolism. Gene Ontology annotations related to this gene include ligase activity and translation factor activity, RNA binding.
Full Name
Glutamyl-TRNA Amidotransferase Subunit B
Function
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Biological Process
Glutaminyl-tRNAGln biosynthesis via transamidation Source: UniProtKB
Mitochondrial translation Source: UniProtKB
Cellular Location
Mitochondrion
Involvement in disease
Combined oxidative phosphorylation deficiency 41 (COXPD41):
An autosomal recessive mitochondrial disorder characterized by prenatal onset, fetal hydrops, intrauterine growth retardation, hypertrophic cardiomyopathy, respiratory insufficiency, lactic acidosis, and decreased activities of mitochondrial respiratory complexes I, III, IV, and V. The disorder is lethal, with death occurring in the perinatal period.
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Anti-GATB antibodies

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Mouse Anti-GATB Recombinant Antibody (6B2) (CBMAB-A6577-LY)

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Target: GATB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 6B2
Application*: WB, E
Datasheet SDS

Mouse Anti-GATB Recombinant Antibody (CBLG1-046) (CBMAB-G0240-LY)

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Target: GATB
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBLG1-046
Application*: E, WB
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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