GYS1

The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Full Name
Glycogen Synthase 1
Function
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
Biological Process
Glycogen biosynthetic process Source: UniProtKB
Heart development Source: Ensembl
Cellular Location
Cytosol; Cytoplasm; Inclusion body; Membrane
Involvement in disease
Muscle glycogen storage disease 0 (GSD0b):
Metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.
PTM
Phosphorylation at Ser-8 by AMPK inactivates the enzyme activity. Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B (By similarity). Phosphorylated at Ser-641 by DYRK2, leading to inactivation (By similarity). Phosphorylated at Ser-641 by PASK, leading to inactivation; phosphorylation by PASK is inhibited by glycogen. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme.
View more

Anti-GYS1 antibodies

+ Filters
Loading...

Rabbit Anti-GYS1 (phosphorylated Ser641) Recombinant Antibody (CBNH-142) (CBMAB-R4467-CN)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBNH-142
Application*: E, WB, IF
Datasheet SDS

Rabbit Anti-GYS1 (Phosphorylated S641) Recombinant Antibody (PTM-CBMAB-0899LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Application*: WB, P, IF/IC, IP
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (CBLG1-2196) (CBMAB-G5895-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2196
Application*: E, F
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (CBLG1-2195) (CBMAB-G5894-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2195
Application*: IC, IF, IH, IP, WB
Datasheet SDS

Mouse Anti-GYS1 Recombinant Antibody (CBLG1-2194) (CBMAB-G5893-LY)

Go to compareCompare
Target: GYS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2194
Application*: E, WB
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (CBLG1-2193) (CBMAB-G5892-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBLG1-2193
Application*: WB
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (CBLG1-2192) (CBMAB-G5891-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-2192
Application*: E, F
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (J.18.5) (CBMAB-G5890-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: J.18.5
Application*: P, IP, WB
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (CBLG1-3057) (CBMAB-G5889-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBLG1-3057
Application*: P, WB
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (7i21) (CBMAB-G5887-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 7i21
Application*: F
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (7H2215B1) (CBMAB-G5886-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 7H2215B1
Application*: E, IH, IP, WB
Datasheet SDS

Mouse Anti-GYS1 Recombinant Antibody (3A7) (CBMAB-G5884-LY)

Go to compareCompare
Target: GYS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A7
Application*: E, WB
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (15B1) (CBMAB-G5883-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 15B1
Application*: WB
Datasheet SDS

Mouse Anti-GYS1 Recombinant Antibody (13B364) (CBMAB-G5882-LY)

Go to compareCompare
Target: GYS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13B364
Application*: E, F
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (CBLG1-3055) (CBMAB-G0974-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Human
Clone: CBLG1-3055
Application*: WB
Datasheet SDS

Rabbit Anti-GYS1 Recombinant Antibody (CBLG1-3054) (CBMAB-G0973-LY)

Go to compareCompare
Target: GYS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-3054
Application*: IC/IF
Datasheet SDS

Mouse Anti-GYS1 Recombinant Antibody (CBFYH-0552) (CBMAB-H1434-FY)

Go to compareCompare
Target: GYS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0552
Application*: E, WB
Datasheet SDS

Mouse Anti-GYS1 Recombinant Antibody (CBT626) (V2LY-0625-LY3381)

Go to compareCompare
Target: GYS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT626
Application*: WB, F, E
Datasheet SDS

Mouse Anti-GYS1 Recombinant Antibody (CBT4154) (V2LY-0625-LY2571)

Go to compareCompare
Target: GYS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4154
Application*: WB, F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry