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HOXB6

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq]

Full Name

HOXB6

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Biological Process

Anterior/posterior pattern specification Source: GO_Central
Embryonic skeletal system morphogenesis Source: Ensembl
Erythrocyte homeostasis Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

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Anti-HOXB6 antibodies

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Mouse Anti-HOXB6 Recombinant Antibody (8E3) (CBMAB-A4042-LY)

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Target: HOXB6

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 8E3

Application*: WB, E

Mouse Anti-HOXB6 (AA 1-57) Recombinant Antibody (CBFYH-1771) (CBMAB-H2780-FY)

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Target: HOXB6

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYH-1771

Application*: E, WB

Mouse Anti-HOXB6 Antibody (1A4) (CBMAB-0501-YC)

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Target: HOXB6

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1A4

Application*: IP, M

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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