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HSPBP1

HSPBP1 (HSPA (Hsp70) Binding Protein 1) is a Protein Coding gene. Diseases associated with HSPBP1 include Long Qt Syndrome 2. Among its related pathways are Protein processing in endoplasmic reticulum and Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF). Gene Ontology (GO) annotations related to this gene include binding and enzyme inhibitor activity.

Full Name

HSPA (Hsp70) Binding Protein 1

Function

Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

Biological Process

Positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: BHF-UCL
Positive regulation of protein ubiquitination Source: BHF-UCL
Protein folding Source: ProtInc

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Anti-HSPBP1 antibodies

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Mouse Anti-HSPBP1 Recombinant Antibody (CBXF-1003) (CBMAB-F1463-CQ)

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Target: HSPBP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-1003

Application*: WB, IC, P, C, E

Mouse Anti-HSPBP1 Recombinant Antibody (CBFYH-2417) (CBMAB-H3429-FY)

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Target: HSPBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2417

Application*: F

Mouse Anti-HSPBP1 Recombinant Antibody (CBFYH-2415) (CBMAB-H3427-FY)

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Target: HSPBP1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYH-2415

Application*: F, IF, P, WB

Mouse Anti-HSPBP1 Recombinant Antibody (CBFYH-2413) (CBMAB-H3425-FY)

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Target: HSPBP1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYH-2413

Application*: WB, IH, IF, F

Mouse Anti-HSPBP1 Recombinant Antibody (CBFYH-2412) (CBMAB-H3424-FY)

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Target: HSPBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey

Clone: CBFYH-2412

Application*: WB, IH, F

Mouse Anti-HSPBP1 Recombinant Antibody (CBFYH-2411) (CBMAB-H3423-FY)

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Target: HSPBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2411

Application*: IF, WB

Mouse Anti-HSPBP1 Recombinant Antibody (CBFYH-2410) (CBMAB-H3422-FY)

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Target: HSPBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-2410

Application*: F, IF, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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