IL17B
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. [provided by RefSeq]
Full Name
interleukin 17B
Function
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.
Biological Process
Cell-cell signaling Source: ProtInc
Immune response Source: ProtInc
Inflammatory response Source: InterPro
Positive regulation of cytokine production involved in inflammatory response Source: Ensembl
Immune response Source: ProtInc
Inflammatory response Source: InterPro
Positive regulation of cytokine production involved in inflammatory response Source: Ensembl
Cellular Location
Secreted
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Anti-IL17B antibodies
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CompareTarget: IL17B
Sensitivity: 0.00021 ng/mL
Detection Range: 0.0005-0.15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: IL17B
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-180
Tag: hFc Tag
Target: IL17B
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-180
Tag: hFc Tag
Target: IL17B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I1319
Application*: E, WB
Target: IL17B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-I1201
Application*: E, WB
Target: IL17B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 7H3
Application*: F
Target: IL17B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0338
Application*: WB, F, MC
Target: IL17B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 174113
Application*: WB, IS, MC, E
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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