INHBC

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate. [provided by RefSeq, Aug 2016]
Full Name
Inhibin Beta C Subunit
Function
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Biological Process
Positive regulation of pathway-restricted SMAD protein phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
SMAD protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
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Anti-INHBC antibodies

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Mouse Anti-INHBC Recombinant Antibody (1) (CBMAB-A4499-YC)

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Target: INHBC
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: 1
Application*: WB, E, P, IC, IF
Datasheet SDS

Mouse Anti-INHBC Recombinant Antibody (A629) (CBMAB-AP3811LY)

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Target: INHBC
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A629
Application*: ICC, IHC, IP, WB
Datasheet SDS

Mouse Anti-INHBC Recombinant Antibody (CBYY-I0960) (CBMAB-I2128-YY)

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Target: INHBC
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0960
Application*: WB
Datasheet SDS

Mouse Anti-INHBC Recombinant Antibody (betaC clone 1) (CBMAB-I1999-YY)

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Target: INHBC
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: betaC clone 1
Application*: E, P, WB, IP
Datasheet SDS

Mouse Anti-INHBC Recombinant Antibody (9H18) (CBMAB-A4502-YC)

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Target: INHBC
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9H18
Application*: E, WB
Datasheet SDS

Mouse Anti-INHBC Recombinant Antibody (14L9) (CBMAB-A4500-YC)

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Target: INHBC
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 14L9
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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