KY

The protein encoded by this gene belongs to the transglutaminase-like superfamily. The protein is involved in the function, maturation and stabilization of the neuromuscular junction and may be required for normal muscle growth. Mutations in this gene are associated with myopathy, myofibrillar, 7. [provided by RefSeq, Apr 2017]
Full Name
Kyphoscoliosis Peptidase
Function
Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC (By similarity).
Biological Process
Cytoplasm, cytoskeleton
Cytoplasm, myofibril, sarcomere, Z line
Cellular Location
Myopathy, myofibrillar, 7 (MFM7):
A form of myofibrillar myopathy, a group of chronic neuromuscular disorders characterized at ultrastructural level by disintegration of the sarcomeric Z disk and myofibrils, and replacement of the normal myofibrillar markings by small dense granules, or larger hyaline masses, or amorphous material. MFM7 is an autosomal recessive form, clinically characterized by early childhood onset of slowly progressive muscle weakness and mild atrophy primarily affecting the lower limbs, associated with joint contractures.
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Anti-KY antibodies

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Mouse Anti-KY Recombinant Antibody (10B499) (CBMAB-K2085-LY)

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Target: KY
Host: Mouse
Antibody Isotype: IgM
Specificity: Sheep
Clone: 10B499
Application*: F, IH
Datasheet SDS

Mouse Anti-KY Recombinant Antibody (76-7-4) (CBMAB-K0223-LY)

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Target: KY
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Pig
Clone: 76-7-4
Application*: F, C, IP
Datasheet SDS

Mouse Anti-KY Recombinant Antibody (5K103) (CBMAB-K0222-LY)

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Target: KY
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Pig
Clone: 5K103
Application*: F, IH
Datasheet SDS

Mouse Anti-KY Recombinant Antibody (10B498) (CBMAB-K0221-LY)

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Target: KY
Host: Mouse
Antibody Isotype: IgG1
Specificity: Sheep
Clone: 10B498
Application*: F, IH, IP
Datasheet SDS

Mouse Anti-KY Recombinant Antibody (RIV12) (CBMAB-K2087-LY)

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Target: KY
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: RIV12
Application*: E, F, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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