MEAK7

MEAK7 functions in negative regulation of oxidative stress-induced neuron death.
Full Name
MTOR Associated Protein, Eak-7 Homolog
Function
Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration (PubMed:29750193).

Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193).
Biological Process
Negative regulation of oxidative stress-induced neuron death Source: Ensembl
Positive regulation of protein localization to lysosome Source: UniProtKB
Regulation of cell migration Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Response to amino acid Source: UniProtKB
Response to insulin Source: UniProtKB
Response to nutrient levels Source: UniProtKB
TOR signaling Source: UniProtKB
Cellular Location
Lysosome
Cytoplasm
Other locations
Membrane
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Anti-MEAK7 antibodies

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Mouse Anti-MEAK7 Recombinant Antibody (12B1) (CBMAB-K2210-LY)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12B1
Application*: WB, IH, IF
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (CBYJT-1454) (CBMAB-T0485-YJ)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-1454
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (CBYJT-1452) (CBMAB-T0483-YJ)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-1452
Application*: IF, P, WB
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (CBYJT-1451) (CBMAB-T0482-YJ)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1451
Application*: IF, P, WB
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (7E4) (CBMAB-K2216-LY)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7E4
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (5D9) (CBMAB-K2215-LY)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5D9
Application*: WB, IH, IC/IF, P
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (3C4) (CBMAB-K2214-LY)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3C4
Application*: IC/IF, IH, P, WB
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (3B1) (CBMAB-K2213-LY)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3B1
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (13H6) (CBMAB-K2212-LY)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H6
Application*: IC/IF, IH, P, WB
Datasheet SDS

Mouse Anti-MEAK7 Recombinant Antibody (12G10) (CBMAB-K2211-LY)

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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 12G10
Application*: IF, P, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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