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MEAK7

MEAK7 functions in negative regulation of oxidative stress-induced neuron death.
Full Name
MTOR Associated Protein, Eak-7 Homolog
Function
Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration (PubMed:29750193).

Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193).
Biological Process
Negative regulation of oxidative stress-induced neuron death Source: Ensembl
Positive regulation of protein localization to lysosome Source: UniProtKB
Regulation of cell migration Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Response to amino acid Source: UniProtKB
Response to insulin Source: UniProtKB
Response to nutrient levels Source: UniProtKB
TOR signaling Source: UniProtKB
Cellular Location
Lysosome
Cytoplasm
Other locations
Membrane

Anti-MEAK7 antibodies

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Mouse Anti-MEAK7 Recombinant Antibody (12B1) (CBMAB-K2210-LY)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12B1
Application*: WB, IH, IF

Mouse Anti-MEAK7 Recombinant Antibody (12G10) (CBMAB-K2211-LY)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 12G10
Application*: IF, P, WB

Mouse Anti-MEAK7 Recombinant Antibody (13H6) (CBMAB-K2212-LY)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H6
Application*: IC/IF, IH, P, WB

Mouse Anti-MEAK7 Recombinant Antibody (3B1) (CBMAB-K2213-LY)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3B1
Application*: F, IF, WB

Mouse Anti-MEAK7 Recombinant Antibody (3C4) (CBMAB-K2214-LY)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3C4
Application*: IC/IF, IH, P, WB

Mouse Anti-MEAK7 Recombinant Antibody (5D9) (CBMAB-K2215-LY)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5D9
Application*: WB, IH, IC/IF, P

Mouse Anti-MEAK7 Recombinant Antibody (7E4) (CBMAB-K2216-LY)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7E4
Application*: IF, IH, WB

Mouse Anti-MEAK7 Recombinant Antibody (CBYJT-1451) (CBMAB-T0482-YJ)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1451
Application*: IF, P, WB

Mouse Anti-MEAK7 Recombinant Antibody (CBYJT-1452) (CBMAB-T0483-YJ)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-1452
Application*: IF, P, WB

Mouse Anti-MEAK7 Recombinant Antibody (CBYJT-1454) (CBMAB-T0485-YJ)

Datasheet SDS
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-1454
Application*: F, IF, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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