MEAK7
MEAK7 functions in negative regulation of oxidative stress-induced neuron death.
Full Name
MTOR Associated Protein, Eak-7 Homolog
Function
Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration (PubMed:29750193).
Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193).
Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193).
Biological Process
Negative regulation of oxidative stress-induced neuron death Source: Ensembl
Positive regulation of protein localization to lysosome Source: UniProtKB
Regulation of cell migration Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Response to amino acid Source: UniProtKB
Response to insulin Source: UniProtKB
Response to nutrient levels Source: UniProtKB
TOR signaling Source: UniProtKB
Positive regulation of protein localization to lysosome Source: UniProtKB
Regulation of cell migration Source: UniProtKB
Regulation of cell population proliferation Source: UniProtKB
Response to amino acid Source: UniProtKB
Response to insulin Source: UniProtKB
Response to nutrient levels Source: UniProtKB
TOR signaling Source: UniProtKB
Cellular Location
Lysosome
Cytoplasm
Other locations
Membrane
Cytoplasm
Other locations
Membrane
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Anti-MEAK7 antibodies
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Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12B1
Application*: WB, IH, IF
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJT-1454
Application*: F, IF, WB
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJT-1452
Application*: IF, P, WB
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1451
Application*: IF, P, WB
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7E4
Application*: IF, IH, WB
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5D9
Application*: WB, IH, IC/IF, P
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3C4
Application*: IC/IF, IH, P, WB
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3B1
Application*: F, IF, WB
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H6
Application*: IC/IF, IH, P, WB
Target: MEAK7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 12G10
Application*: IF, P, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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