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MUC12

This gene encodes an integral membrane glycoprotein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces and have been implicated in epithelial renewal and differentiation. These glycoproteins also play a role in intracellular signaling. This protein is expressed on the apical membrane surface of epithelial cells that line the mucosal surfaces of many different tissues including the colon, pancreas, prostate, and uterus. The expression of this gene is downregulated in colorectal cancer tissue.
Full Name
mucin 12, cell surface associated
Function
Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium.
Biological Process
Regulation of cell growth Source: UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 17-5380
Helical: 5381-5401
Cytoplasmic: 5402-5478
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Anti-MUC12 antibodies

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Mouse Anti-MUC12 (AA 31-120) Recombinant Antibody (CBFYM-2791) (CBMAB-M2984-FY)

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Target: MUC12
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2791
Application*: E, WB
Datasheet SDS

Mouse Anti-MUC12 (AA 1-862) Recombinant Antibody (CBFYM-2790) (CBMAB-M2983-FY)

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Target: MUC12
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-2790
Application*: WB
Datasheet SDS

Mouse Anti-MUC12 (AA 1-919) Recombinant Antibody (CBFYM-2789) (CBMAB-M2982-FY)

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Target: MUC12
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-2789
Application*: WB, IP
Datasheet SDS

Mouse Anti-MUC12 Recombinant Antibody (CBT3919) (V2LY-0625-LY1676)

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Target: MUC12
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT3919
Application*: IC, F
Datasheet SDS

Mouse Anti-MUC12 Recombinant Antibody (CBT3020) (V2LY-0625-LY1674)

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Target: MUC12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3020
Application*: IH, F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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