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NR2F1

The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS). [provided by RefSeq, Apr 2014]
Full Name
NR2F1
Function
Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5'-AGGTCA-3' motif. Represses transcriptional activity of LHCG.
Biological Process
Anatomical structure developmentManual Assertion Based On ExperimentIBA:GO_Central
Cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of neuron projection developmentIEA:Ensembl
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Nervous system developmentIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
Involvement in disease
Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS):
An autosomal dominant disorder characterized by optic atrophy associated with developmental delay and intellectual disability. Most patients also have evidence of cerebral visual impairment.
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Anti-NR2F1 antibodies

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Mouse Anti-NR2F1 Recombinant Antibody (CBWJC-4262) (CBMAB-C5619WJ)

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Target: NR2F1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBWJC-4262
Application*: WB, IH, IP
Datasheet SDS

Rabbit Anti-NR2F1 Recombinant Antibody (CBWJC-4261) (CBMAB-C5618WJ)

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Target: NR2F1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJC-4261
Application*: WB, IP
Datasheet SDS

Rabbit Anti-NR2F1 Recombinant Antibody (CBWJC-2350) (CBMAB-C3295WJ)

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Target: NR2F1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJC-2350
Application*: WB, P, F, IC
Datasheet SDS

Mouse Anti-NR2F1 Recombinant Antibody (CBYY-C2937) (CBMAB-C4380-YY)

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Target: NR2F1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2937
Application*: WB, D
Datasheet SDS

Mouse Anti-NR2F1 Recombinant Antibody (CBXC-1365) (CBMAB-C4259-CQ)

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Target: NR2F1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-1365
Application*: WB, IH, IP, E
Datasheet SDS

Mouse Anti-NR2F1 Recombinant Antibody (CBWJN-1534) (CBMAB-N3420-WJ)

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Target: NR2F1
Host: Mouse
Specificity: Human
Clone: CBWJN-1534
Application*: WB
Datasheet SDS

Mouse Anti-NR2F1 Recombinant Antibody (CBWJN-0400) (CBMAB-N3419-WJ)

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Target: NR2F1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0400
Application*: DB, WB
Datasheet SDS

Mouse Anti-NR2F1 Recombinant Antibody (1A4) (CBMAB-N3418-WJ)

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Target: NR2F1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1A4
Application*: E, WB
Datasheet SDS

Mouse Anti-NR2F1 Recombinant Antibody (#H8132) (CBMAB-1633-CN)

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Target: NR2F1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: #H8132
Application*: WB, IH, IP
Datasheet SDS

Mouse Anti-NR2F1 Recombinant Antibody (451C3a) (CBMAB-1632-CN)

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Target: NR2F1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 451C3a
Application*: WB, DB
Datasheet SDS

Mouse Anti-NR2F1 Antibody (1D5) (CBMAB-0755-YC)

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Target: NR2F1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Common fruit fly
Clone: 1D5
Application*: E, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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