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OSCAR

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Full Name
Osteoclast Associated, Immunoglobulin-Like Receptor
Function
Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.
Biological Process
Osteoclast differentiationManual Assertion Based On ExperimentIMP:MGI
Cellular Location
Isoform 1
Secreted
Isoform 2
Cell membrane
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Anti-OSCAR antibodies

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Recombinant Rat Anti-OSCAR Antibody (CBHb093) (CBMAB-Hb846-LY)

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Target: OSCAR
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBHb093
Application*: FC, FuncS
Datasheet SDS

Rat Anti-OSCAR Recombinant Antibody (CBFYA-0064) (CBMAB-X0095-FY)

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Target: OSCAR
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYA-0064
Application*: F, FN
Datasheet SDS

Mouse Anti-OSCAR Recombinant Antibody (CBXO-0243) (CBMAB-O0607-CQ)

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Target: OSCAR
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXO-0243
Application*: WB
Datasheet SDS

Rat Anti-OSCAR Recombinant Antibody (CBXO-0496) (CBMAB-O0605-CQ)

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Target: OSCAR
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXO-0496
Application*: WB
Datasheet SDS

Mouse Anti-OSCAR Recombinant Antibody (6S6) (CBMAB-O0604-CQ)

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Target: OSCAR
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 6S6
Application*: WB
Datasheet SDS

Mouse Anti-OSCAR Recombinant Antibody (CBXO-0440) (CBMAB-O0603-CQ)

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Target: OSCAR
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXO-0440
Application*: WB
Datasheet SDS

Rat Anti-OSCAR Recombinant Antibody (5B8) (CBMAB-O0602-CQ)

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Target: OSCAR
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 5B8
Application*: F, FN
Datasheet SDS

Human Anti-OSCAR Recombinant Antibody (CBXO-0434) (CBMAB-O0074-CQ)

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Target: OSCAR
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXO-0434
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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