P2RX5

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Full Name
purinergic receptor P2X, ligand-gated ion channel, 5
Function
Receptor for ATP that acts as a ligand-gated ion channel.
Biological Process
Nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of calcium ion transport into cytosol1 PublicationNAS:BHF-UCL
Positive regulation of calcium-mediated signaling1 PublicationNAS:BHF-UCL
Response to ATPIEA:InterPro
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Cytoplasmic: 1-30
Helical: 31-51
Extracellular: 52-319
Helical: 320-340
Cytoplasmic: 341-422
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Anti-P2RX5 antibodies

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Mouse Anti-P2RX5 Recombinant Antibody (1C5) (CBMAB-P0585-YC)

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Target: P2RX5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C5
Application*: E, RNAi, WB
Datasheet SDS

Mouse Anti-P2RX5 Recombinant Antibody (A-11) (CBMAB-P0587-YC)

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Target: P2RX5
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: A-11
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-P2RX5 Recombinant Antibody (2A2A6) (CBMAB-P0586-YC)

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Target: P2RX5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Pig, Rat
Clone: 2A2A6
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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