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PBX2

This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. [provided by RefSeq]

Full Name

PBX2

Function

Transcriptional activator that binds the sequence 5'-ATCAATCAA-3'. Activates transcription of PF4 in complex with MEIS1.

Biological Process

Animal organ morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
Brain developmentManual Assertion Based On ExperimentIBA:GO_Central
Embryonic limb morphogenesisIEA:Ensembl
Embryonic organ developmentManual Assertion Based On ExperimentIBA:GO_Central
Eye developmentManual Assertion Based On ExperimentIBA:GO_Central
Neuron developmentManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Proximal/distal pattern formationIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

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Anti-PBX2 antibodies

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Mouse Anti-PBX2 Recombinant Antibody (CBYC-P191) (CBMAB-P0933-YC)

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Target: PBX2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYC-P191

Application*: WB, RNAi, E, WB, IF

Mouse Anti-PBX2 Recombinant Antibody (CBYC-P190) (CBMAB-P0932-YC)

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Target: PBX2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYC-P190

Application*: E, IC, WB

Mouse Anti-PBX2 Recombinant Antibody (H-7) (CBMAB-P0931-YC)

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Target: PBX2

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: H-7

Application*: WB, IP, IF, E

Mouse Anti-PBX2 Recombinant Antibody (2E9) (CBMAB-P0930-YC)

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Target: PBX2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2E9

Application*: IF, WB

Mouse Anti-PBX2 Recombinant Antibody (156C1_2a) (CBMAB-P0929-YC)

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Target: PBX2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 156C1_2a

Application*: DB, IC

Mouse Anti-PBX2 Antibody (1C4) (CBMAB-0787-YC)

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Target: PBX2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1C4

Application*: E, IP

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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