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PCYT1B

The protein encoded by this gene belongs to the cytidylyltransferase family. It is involved in the regulation of phosphatidylcholine biosynthesis. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Full Name

Phosphate Cytidylyltransferase 1, Choline, Beta

Function

Isoform 1
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Isoform 2
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

Biological Process

CDP-choline pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Ovarian follicle developmentIEA:Ensembl
Phosphatidylcholine biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
SpermatogenesisIEA:Ensembl

Cellular Location

Isoform 1
Cytoplasm
Endoplasmic reticulum
Isoform 2
Endoplasmic reticulum

PTM

Isoform 1
Phosphorylated.
Isoform 2
Extensively phosphorylated.

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Anti-PCYT1B antibodies

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Mouse Anti-PCYT1B Recombinant Antibody (CBXC-0685) (CBMAB-C5914-CQ)

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Target: PCYT1B

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXC-0685

Application*: SE, E, WB, IF

Mouse Anti-PCYT1B Recombinant Antibody (F39 P7 F11) (CBMAB-P1121-YC)

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Target: PCYT1B

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: F39 P7 F11

Application*: WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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