PCYT1B
The protein encoded by this gene belongs to the cytidylyltransferase family. It is involved in the regulation of phosphatidylcholine biosynthesis. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Full Name
Phosphate Cytidylyltransferase 1, Choline, Beta
Function
Isoform 1
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Isoform 2
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Isoform 2
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Biological Process
CDP-choline pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Ovarian follicle developmentIEA:Ensembl
Phosphatidylcholine biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
SpermatogenesisIEA:Ensembl
Ovarian follicle developmentIEA:Ensembl
Phosphatidylcholine biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
SpermatogenesisIEA:Ensembl
Cellular Location
Isoform 1
Cytoplasm
Endoplasmic reticulum
Isoform 2
Endoplasmic reticulum
Cytoplasm
Endoplasmic reticulum
Isoform 2
Endoplasmic reticulum
PTM
Isoform 1
Phosphorylated.
Isoform 2
Extensively phosphorylated.
Phosphorylated.
Isoform 2
Extensively phosphorylated.
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Anti-PCYT1B antibodies
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Target: PCYT1B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-0685
Application*: SE, E, WB, IF
Target: PCYT1B
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: F39 P7 F11
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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