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PDE4C

PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Full Name

phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)

Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Biological Process

cAMP catabolic processIEA:UniProtKB-UniPathway
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell projection, cilium

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Anti-PDE4C antibodies

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Mouse Anti-PDE4C Recombinant Antibody (6A10) (CBMAB-P1217-YC)

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Target: PDE4C

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 6A10

Application*: E, WB

Mouse Anti-PDE4C Recombinant Antibody (4E5) (CBMAB-P1216-YC)

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Target: PDE4C

Host: Mouse

Antibody Isotype: IgG3, κ

Specificity: Human

Clone: 4E5

Application*: E, IF, WB

Human Recombinant PDE4C, Active protein, GST Tag (V2LY-0526-LY6035)

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Target: PDE4C

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: 287-end

Tag: GST Tag

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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