Mouse Anti-PDE4C Recombinant Antibody (4E5) (CBMAB-P1216-YC)

Name: Mouse Anti-PDE4C Recombinant Antibody (4E5)
SKU: CBMAB-P1216-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

4E5

Application

ELISA, IF, WB

Immunogen

PDE4C (NP_000914, 1-99 aa) partial recombinant protein with GST tag. Immunogen sequence: MENLGVGEGA EACSRLSRSR GRHSMTRAPK HLWRQPRRPI RIQQRFYSDP DKSAGCRERD LSPRPELRKS RLSWPVSSCR RFDLENGLSC GRRALDPQS

Specificity

Human

Antibody Isotype

IgG3, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 1-99

More Infomation

Target

Full Name

phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)

Introduction

PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Entrez Gene ID

5143

UniProt ID

Q08493

Alternative Names

Phosphodiesterase 4C; DPDE1; PDE21; Phosphodiesterase 4C, CAMP-Specific (Dunce (Drosophila)-Homolog Phosphodiesterase E1); Phosphodiesterase 4C, CAMP-Specific (Phosphodiesterase E1 Dunce Homolog, Drosophila); Phosphodiesterase E1 Dunce Homolog (Drosophila); CAMP-Specific 3,5-Cyclic Phosphodiesterase 4C;

Function

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Biological Process

cAMP catabolic processIEA:UniProtKB-UniPathway
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell projection, cilium

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-PDE4C Recombinant Antibody (6A10) (CAT#: CBMAB-P1217-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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