Phospho-JUNB (Thr102/Thr104)

Full Name

Function

Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[GC]TCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity (By similarity).

Biological Process

Cellular response to calcium ionIEA:Ensembl
DecidualizationIEA:Ensembl
Embryonic process involved in female pregnancyIEA:Ensembl
Labyrinthine layer blood vessel developmentIEA:Ensembl
Osteoblast differentiationIEA:Ensembl
Osteoblast proliferationIEA:Ensembl
Osteoclast differentiationIEA:Ensembl
Positive regulation of cell differentiationIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:CAFA
Regulation of cell cycleManual Assertion Based On ExperimentIBA:GO_Central
Regulation of cell population proliferationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Trophectodermal cell differentiationIEA:Ensembl
VasculogenesisIEA:Ensembl

Cellular Location

Nucleus

PTM

Ubiquitinated by ITCH, leading to its degradation.