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PKIG

The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive PKA inhibitor, and is a predominant form of PKA inhibitors in various tissues. Three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]

Full Name

protein kinase (cAMP-dependent, catalytic) inhibitor gamma

Function

Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

Biological Process

Negative regulation of cAMP-dependent protein kinase activityManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of protein import into nucleusIEA:Ensembl
Negative regulation of transcription by RNA polymerase IIIEA:Ensembl

Cellular Location

cytoplasm
nucleus

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Anti-PKIG antibodies

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Mouse Anti-PKIG Recombinant Antibody (D-8) (CBMAB-P1927-YC)

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Target: PKIG

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: D-8

Application*: WB, IP, IF, E

Mouse Anti-PKIG Recombinant Antibody (2D9) (CBMAB-P1926-YC)

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Target: PKIG

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2D9

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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