PKIG

The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive PKA inhibitor, and is a predominant form of PKA inhibitors in various tissues. Three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]

Full Name

protein kinase (cAMP-dependent, catalytic) inhibitor gamma

Function

Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

Biological Process

Negative regulation of cAMP-dependent protein kinase activityManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of protein import into nucleusIEA:Ensembl
Negative regulation of transcription by RNA polymerase IIIEA:Ensembl

Cellular Location

cytoplasm
nucleus

Anti-PKIG antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-PKIG Recombinant Antibody (D-8) (CBMAB-P1927-YC)

Datasheet

SDS

Target: PKIG

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: D-8

Application*: WB, IP, IF, E

Mouse Anti-PKIG Recombinant Antibody (2D9) (CBMAB-P1926-YC)

Datasheet

SDS

Target: PKIG

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2D9

Application*: E, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)