PLET1
PLET1 (Placenta Expressed Transcript 1) is a protein coding gene. Among its related pathways are Metabolism of proteins and Post-translational modification-synthesis of GPI-anchored proteins.
Full Name
Placenta expressed transcript 1
Function
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle (By similarity).
Biological Process
Cell differentiationIEA:UniProtKB-KW
Negative regulation of cell-matrix adhesionISS:UniProtKB
Positive regulation of cell migrationISS:UniProtKB
Wound healing, spreading of epidermal cellsISS:UniProtKB
Negative regulation of cell-matrix adhesionISS:UniProtKB
Positive regulation of cell migrationISS:UniProtKB
Wound healing, spreading of epidermal cellsISS:UniProtKB
Cellular Location
Apical cell membrane
Localized at the apical membrane of the most differentiated keratinocytes of the outer root sheath (ORS), clustered mainly in planar regions of the plasma membrane at the base of microvilli.
Localized at the apical membrane of the most differentiated keratinocytes of the outer root sheath (ORS), clustered mainly in planar regions of the plasma membrane at the base of microvilli.
PTM
N-glycosylated.
GPI-anchored.
GPI-anchored.
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Anti-PLET1 antibodies
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Target: PLET1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBYC-P438
Application*: F
Target: Plet1
Sensitivity: 0.0055 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: PLET1
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: 33A10
Application*: F, IF, C, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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