PPP3R2

Full Name

PPP3R2

Function

Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

Biological Process

Calcineurin-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of calcium ion import across plasma membrane1 PublicationIC:ComplexPortal
Negative regulation of voltage-gated calcium channel activity1 PublicationIC:ComplexPortal
Penetration of zona pellucidaIEA:Ensembl
Positive regulation of calcineurin-NFAT signaling cascade2 PublicationsIC:ComplexPortal
Positive regulation of calcium ion import across plasma membrane1 PublicationIC:ComplexPortal
Positive regulation of voltage-gated calcium channel activity1 PublicationIC:ComplexPortal
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Mitochondrion
Localizes in the mitochondria in a SPATA33-dependent manner.

Anti-PPP3R2 antibodies

Mouse Anti-PPP3R2 Recombinant Antibody (5D9) (CBMAB-A6988-LY)

Datasheet

SDS

Target: PPP3R2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 5D9

Application*: WB, E

PPP3R2 Matched Antibody Pair (921) (APMAB-921LY)

Datasheet

SDS

Target: PPP3R2

Specificity: Human

PPP3R2 Matched Antibody Pair (920) (APMAB-920LY)

Datasheet

SDS

Target: PPP3R2

Specificity: Human

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)