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PPP3R2

Full Name

PPP3R2

Function

Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

Biological Process

Calcineurin-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of calcium ion import across plasma membrane1 PublicationIC:ComplexPortal
Negative regulation of voltage-gated calcium channel activity1 PublicationIC:ComplexPortal
Penetration of zona pellucidaIEA:Ensembl
Positive regulation of calcineurin-NFAT signaling cascade2 PublicationsIC:ComplexPortal
Positive regulation of calcium ion import across plasma membrane1 PublicationIC:ComplexPortal
Positive regulation of voltage-gated calcium channel activity1 PublicationIC:ComplexPortal
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Mitochondrion
Localizes in the mitochondria in a SPATA33-dependent manner.

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Anti-PPP3R2 antibodies

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Mouse Anti-PPP3R2 Recombinant Antibody (5D9) (CBMAB-A6988-LY)

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Target: PPP3R2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 5D9

Application*: WB, E

PPP3R2 Matched Antibody Pair (921) (APMAB-921LY)

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Target: PPP3R2

Specificity: Human

PPP3R2 Matched Antibody Pair (920) (APMAB-920LY)

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Target: PPP3R2

Specificity: Human

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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