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Mouse Anti-PPP3R2 Recombinant Antibody (5D9) (CBMAB-A6988-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
5D9
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
PPP3R2 (NP_671709, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
PPP3R2
Entrez Gene ID
5535
UniProt ID
Q96LZ3
Alternative Names
PPP3RL
Function
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
Biological Process
Calcineurin-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of calcium ion import across plasma membrane1 PublicationIC:ComplexPortal
Negative regulation of voltage-gated calcium channel activity1 PublicationIC:ComplexPortal
Penetration of zona pellucidaIEA:Ensembl
Positive regulation of calcineurin-NFAT signaling cascade2 PublicationsIC:ComplexPortal
Positive regulation of calcium ion import across plasma membrane1 PublicationIC:ComplexPortal
Positive regulation of voltage-gated calcium channel activity1 PublicationIC:ComplexPortal
Protein dephosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Mitochondrion
Localizes in the mitochondria in a SPATA33-dependent manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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