REEP5

REEP5 (Receptor Accessory Protein 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. An important paralog of this gene is REEP6.

Full Name

Receptor Accessory Protein 5

Function

Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.

Biological Process

Biological Process endoplasmic reticulum membrane organizationISS:UniProtKB
Biological Process endoplasmic reticulum organizationISS:FlyBase
Biological Process regulation of intracellular transportISS:FlyBase

Cellular Location

Endoplasmic reticulum membrane
Sarcoplasmic reticulum membrane
Localizes to endoplasmic reticulum tubular network (PubMed:23969831).
In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity).

Topology

Cytoplasmic: 1-34
Helical: 35-51
Lumenal: 52-53
Helical: 54-74
Cytoplasmic: 75-84
Helical: 85-103
Lumenal: 104-105
Helical: 106-123
Cytoplasmic: 124-189

Anti-REEP5 antibodies

Rabbit Anti-REEP5 Recombinant Antibody (BA0092) (CBMAB-0774CQ)

Datasheet

SDS

Target: REEP5

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: BA0092

Application*: WB

Rabbit Anti-REEP5 Recombinant Antibody (BA0011) (CBMAB-0773CQ)

Datasheet

SDS

Target: REEP5

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: BA0011

Application*: WB

Mouse Anti-REEP5 Recombinant Antibody (F-2) (CBMAB-R2030-CN)

Datasheet

SDS

Target: REEP5

Host: Mouse

Specificity: Human

Clone: F-2

Application*: WB, IP, IF, E

Mouse Anti-REEP5 Recombinant Antibody (CBCNR-378) (CBMAB-R2029-CN)

Datasheet

SDS

Target: REEP5

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Frog

Clone: CBCNR-378

Application*: WB, E, IF

Mouse Anti-REEP5 Recombinant Antibody (4D2) (CBMAB-R2026-CN)

Datasheet

SDS

Target: REEP5

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 4D2

Application*: WB, IH, F

Mouse Anti-REEP5 Recombinant Antibody (3G11) (CBMAB-R2025-CN)

Datasheet

SDS

Target: REEP5

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3G11

Application*: E, WB

Mouse Anti-REEP5 Recombinant Antibody (3G11) (CBMAB-A0984-LY)

Datasheet

SDS

Target: REEP5

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3G11

Application*: WB, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)