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Rabbit Anti-REEP5 Recombinant Antibody (BA0092) (CBMAB-0774CQ)

This product is a rabbit antibody that recognizes REEP5. The antibody BA0092 can be used for immunoassay techniques such as: WB.
See all REEP5 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
BA0092
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Synthetic peptide between in Human REEP5
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Receptor Accessory Protein 5
Introduction
REEP5 (Receptor Accessory Protein 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. An important paralog of this gene is REEP6.
Entrez Gene ID
Human7905
Mouse13476
Rat364838
UniProt ID
HumanQ00765
MouseQ60870
RatB2RZ37
Alternative Names
DP1; TB2; YOP1; Yip2e; D5S346; C5orf18
Function
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
Biological Process
Biological Process endoplasmic reticulum membrane organizationISS:UniProtKB
Biological Process endoplasmic reticulum organizationISS:FlyBase
Biological Process regulation of intracellular transportISS:FlyBase
Cellular Location
Endoplasmic reticulum membrane
Sarcoplasmic reticulum membrane
Localizes to endoplasmic reticulum tubular network (PubMed:23969831).
In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity).
Topology
Cytoplasmic: 1-34
Helical: 35-51
Lumenal: 52-53
Helical: 54-74
Cytoplasmic: 75-84
Helical: 85-103
Lumenal: 104-105
Helical: 106-123
Cytoplasmic: 124-189
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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