S100A5
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq]
Full Name
S100 calcium binding protein A5
Function
Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites.
Cellular Location
neuronal cell body
nucleus
nucleus
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Anti-S100A5 antibodies
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Target: S100A5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 5E1
Application*: WB, E
Target: S100A5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-3291
Application*: E, IH, WB
Target: S100A5
Host: Mouse
Specificity: Rat
Clone: CBXS-2503
Application*: E, IC, IH, WB
Target: S100A5
Host: Mouse
Specificity: Human
Clone: CBXS-2502
Application*: E, IC, IH, WB
Target: S100A5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-1126
Application*: E, IF, IF
Target: S100A5
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-1080
Application*: E
Target: S100A5
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-1043
Application*: P
Target: S100A5
Host: Mouse
Specificity: Rat
Clone: CBXS-0083
Application*: WB, IC, P, C, E
Target: S100A5
Host: Mouse
Specificity: Human
Clone: CBXS-0082
Application*: WB, IC, P, C, E
Target: S100A5
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBXS-0081
Application*: E, WB
Target: S100A5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5011
Application*: WB
Target: S100A5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4954
Application*: E
Target: S100A5
Expressed Host: E. coli
Sequence: Amino Acid: 1-93
Tag: His Tag
Target: S100A5
Expressed Host: E. coli
Sequence: Amino Acid: 1-110
Tag: His Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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