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SLC14A1

The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system.

Full Name

Solute Carrier Family 14 Member 1 (Kidd Blood Group)

Function

Mediates the transport of urea driven by a concentration gradient across the cell membrane of erythrocytes (PubMed:7989337, PubMed:10514515, PubMed:7797558, PubMed:8997401).
Also mediates the transport of urea across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism (By similarity).
Facilitates water transport in erythrocytes (By similarity).

Biological Process

Biological Process establishment of localization in cellIEA:Ensembl
Biological Process transmembrane transportTAS:Reactome
Biological Process urea transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process urea transportManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cell membrane
Basolateral cell membrane
Restricted to the basolateral membrane in various portions of the urothelium.

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Anti-SLC14A1 antibodies

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Mouse Anti-SLC14A1 Recombinant Antibody (CBXS-1965) (CBMAB-S0149-CQ)

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Target: SLC14A1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-1965

Application*: F

Human SLC14A1 ELISA Kit (V2LY-0626-LY3767)

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Target: SLC14A1

Sensitivity: 0.043 ng/mL

Detection Range: 0.1-38 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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