loading...

SNRPD1

This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene.

Full Name

Small Nuclear Ribonucleoprotein D1 Polypeptide

Function

Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).
Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).
Is also a component of the minor U12 spliceosome (PubMed:15146077).
May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA (Probable)

Biological Process

Biological Process 7-methylguanosine cap hypermethylation1 PublicationIC:ComplexPortal
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process RNA splicingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process spliceosomal complex assemblyManual Assertion Based On ExperimentTAS:ProtInc
Biological Process spliceosomal snRNP assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process U2-type prespliceosome assembly1 PublicationIC:ComplexPortal

Cellular Location

Cytoplasm, cytosol
Nucleus
SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.

PTM

Methylated on arginine residues by PRMT5 and PRMT7; probable asymmetric dimethylation which is required for assembly and biogenesis of snRNPs.

View more

Anti-SNRPD1 antibodies

+ Filters

Loading...

Mouse Anti-SNRPD1 Recombinant Antibody (ANA128) (CBMAB-S2929-CQ)

Compare

Target: SNRPD1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: ANA128

Application*: IF, IP, WB

Human SNRPD1 ELISA Kit (V2LY-0626-LY5256)

Compare

Target: SNRPD1

Sensitivity: 0.0099 ng/mL

Detection Range: 0.02-4.5 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

Mouse Anti-SNRPD1 Recombinant Antibody (
24E2) (V2LY-0725-LY882)

Compare

Target: SNRPD1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 24E2

Application*: E, IH, IF, F

Mouse Anti-SNRPD1 Recombinant Antibody (CBXS-3446) (CBMAB-S6177-CQ)

Compare

Target: SNRPD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-3446

Application*: DB, WB

Mouse Anti-SNRPD1 Recombinant Antibody (CBXS-0617) (CBMAB-S3559-CQ)

Compare

Target: SNRPD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-0617

Application*: WB

Mouse Anti-SNRPD1 Recombinant Antibody (ANA127) (CBMAB-S2928-CQ)

Compare

Target: SNRPD1

Host: Mouse

Antibody Isotype: IgA, κ

Specificity: Human

Clone: ANA127

Application*: IF, IP, WB

Mouse Anti-SNRPD1 Recombinant Antibody (CBXS-4673) (CBMAB-S1908-CQ)

Compare

Target: SNRPD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4673

Application*: DB, WB

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry