SREK1

This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Full Name

Splicing Regulatory Glutamic Acid And Lysine Rich Protein 1

Function

Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity).

Biological Process

Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process RNA splicingIEA:UniProtKB-KW

Cellular Location

Nucleus

Anti-SREK1 antibodies

Mouse Anti-SREK1 Recombinant Antibody (1D11) (CBMAB-A8033-LY)

Datasheet

SDS

Target: SREK1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1D11

Application*: WB, E

Mouse Anti-SREK1 Recombinant Antibody (CBXS-3961) (CBMAB-S1224-CQ)

Datasheet

SDS

Target: SREK1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBXS-3961

Application*: E, IC, IF, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)