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SREK1

This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Full Name

Splicing Regulatory Glutamic Acid And Lysine Rich Protein 1

Function

Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity).

Biological Process

Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process RNA splicingIEA:UniProtKB-KW

Cellular Location

Nucleus

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Anti-SREK1 antibodies

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Mouse Anti-SREK1 Recombinant Antibody (1D11) (CBMAB-A8033-LY)

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Target: SREK1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1D11

Application*: WB, E

Mouse Anti-SREK1 Recombinant Antibody (CBXS-3961) (CBMAB-S1224-CQ)

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Target: SREK1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBXS-3961

Application*: E, IC, IF, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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