TMOD3
TMOD3 (Tropomodulin 3) is a Protein Coding gene. Among its related pathways are Cardiac conduction and Striated Muscle Contraction. Gene Ontology (GO) annotations related to TMOD3 include actin binding and tropomyosin binding. An important paralog of TMOD3 is TMOD2.
Full Name
tropomodulin 3 (ubiquitous)
Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
Biological Process
Biological Process actin filament organizationSource:GO_Central1 Publication
Biological Process erythrocyte developmentSource:Ensembl
Biological Process mitotic cell cycle phase transitionSource:Ensembl
Biological Process muscle contractionSource:GO_Central1 Publication
Biological Process myofibril assemblySource:GO_Central1 Publication
Biological Process pointed-end actin filament cappingSource:InterPro
Biological Process positive regulation of mitotic cell cycle phase transitionSource:Ensembl
Biological Process erythrocyte developmentSource:Ensembl
Biological Process mitotic cell cycle phase transitionSource:Ensembl
Biological Process muscle contractionSource:GO_Central1 Publication
Biological Process myofibril assemblySource:GO_Central1 Publication
Biological Process pointed-end actin filament cappingSource:InterPro
Biological Process positive regulation of mitotic cell cycle phase transitionSource:Ensembl
Cellular Location
Cytoplasm, cytoskeleton
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Anti-TMOD3 antibodies
+ Filters
Target: TMOD3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E1
Application*: WB, E
Target: TMOD3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJT-3550
Application*: E, WB
Target: TMOD3
Sensitivity: 0.054 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: TMOD3
Sensitivity: 0.042 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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