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Mouse Anti-TMOD3 Recombinant Antibody (CBYJT-3550) (CBMAB-T2876-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TMOD3 (Tropomodulin 3). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all TMOD3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3550
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa280-353 from human TMOD3 (NP_055362) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 280-353

Target

Full Name
tropomodulin 3 (ubiquitous)
Introduction
TMOD3 (Tropomodulin 3) is a Protein Coding gene. Among its related pathways are Cardiac conduction and Striated Muscle Contraction. Gene Ontology (GO) annotations related to TMOD3 include actin binding and tropomyosin binding. An important paralog of TMOD3 is TMOD2.
Entrez Gene ID
29766
UniProt ID
Q9NYL9
Alternative Names
Tropomodulin 3; Ubiquitous Tropomodulin; Tropomodulin 3 (Ubiquitous); Tropomodulin-3; U-Tmod; UTMOD
Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
Biological Process
Biological Process actin filament organizationSource:GO_Central1 Publication
Biological Process erythrocyte developmentSource:Ensembl
Biological Process mitotic cell cycle phase transitionSource:Ensembl
Biological Process muscle contractionSource:GO_Central1 Publication
Biological Process myofibril assemblySource:GO_Central1 Publication
Biological Process pointed-end actin filament cappingSource:InterPro
Biological Process positive regulation of mitotic cell cycle phase transitionSource:Ensembl
Cellular Location
Cytoplasm, cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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