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TREH

This gene encodes an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, plants, and insects. A partial duplication of this gene is located adjacent to this locus on chromosome 11. [provided by RefSeq]

Full Name

trehalase (brush-border membrane glycoprotein)

Function

Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.

Biological Process

Biological Process animal organ morphogenesis Source:Ensembl
Biological Process trehalose catabolic process Source:UniProtKB1 Publication
Biological Process trehalose metabolic process Source:UniProtKB1 Publication

Cellular Location

Cell membrane

Involvement in disease

Trehalase deficiency (TREHD):
An autosomal recessive condition characterized by the inability to digest trehalose, a disaccharide found in mushrooms, products containing baker's yeast, and dried food. Individuals with trehalase deficiency suffer from abdominal pain, increased rectal flatulence, and diarrhea due to osmotic water flow into the colon.

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Anti-TREH antibodies

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Mouse Anti-TREH Recombinant Antibody (2D10) (CBMAB-A9485-LY)

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Target: TREH

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2D10

Application*: WB, E

Mouse Anti-TREH Recombinant Antibody (CBYJT-4593) (CBMAB-T4114-YJ)

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Target: TREH

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-4593

Application*: SE, WB, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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