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Mouse Anti-TREH Recombinant Antibody (CBYJT-4593) (CBMAB-T4114-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4593
Antibody Isotype
IgG2a, κ
Application
S-ELISA, WB, ELISA

Basic Information

Immunogen
TREH (NP_009111.1, 25 a.a. ~ 124 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 25-124

Target

Full Name
trehalase (brush-border membrane glycoprotein)
Introduction
TREH is an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, plants, and insects. A partial duplication of TREH is located adjacent to this locus on chromosome 11.
Entrez Gene ID
11181
UniProt ID
O43280
Alternative Names
Trehalase; Alpha, Alpha-Trehalose Glucohydrolase; Trehalase (Brush-Border Membrane Glycoprotein); Alpha, Alpha-Trehalase; EC 3.2.1.28; TREA; TRE
Function
Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.
Biological Process
Biological Process animal organ morphogenesis Source:Ensembl
Biological Process trehalose catabolic process Source:UniProtKB1 Publication
Biological Process trehalose metabolic process Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Involvement in disease
Trehalase deficiency (TREHD):
An autosomal recessive condition characterized by the inability to digest trehalose, a disaccharide found in mushrooms, products containing baker's yeast, and dried food. Individuals with trehalase deficiency suffer from abdominal pain, increased rectal flatulence, and diarrhea due to osmotic water flow into the colon.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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