UBE2Z

Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE2Z is an E2 enzyme (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM

Full Name

ubiquitin-conjugating enzyme E2Z

Function

Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).
Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.

Biological Process

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:GO_Central1 Publication
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process Source:Ensembl

Cellular Location

Cytoplasm
Nucleus

Anti-UBE2Z antibodies

Mouse Anti-UBE2Z Recombinant Antibody (4B1) (CBMAB-A9734-LY)

Datasheet

SDS

Target: UBE2Z

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4B1

Application*: WB, E

Mouse Anti-UBE2Z Recombinant Antibody (CBFYU-165) (CBMAB-U0165-FY)

Datasheet

SDS

Target: UBE2Z

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYU-165

Application*: E, IF, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)