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UBE2Z

Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE2Z is an E2 enzyme (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM

Full Name

ubiquitin-conjugating enzyme E2Z

Function

Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).
Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.

Biological Process

Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:GO_Central1 Publication
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process Source:Ensembl

Cellular Location

Cytoplasm
Nucleus

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Anti-UBE2Z antibodies

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Human Recombinant UBE2Z protein, His Tag (V2LY-0526-LY7516)

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Target: UBE2Z

Expressed Host: E. coli

Sequence: Amino Acid: 109-end

Tag: His Tag

Mouse Anti-UBE2Z Recombinant Antibody (4B1) (CBMAB-A9734-LY)

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Target: UBE2Z

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4B1

Application*: WB, E

Mouse Anti-UBE2Z Recombinant Antibody (CBFYU-165) (CBMAB-U0165-FY)

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Target: UBE2Z

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYU-165

Application*: E, IF, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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