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Mouse Anti-UBE2Z Recombinant Antibody (4B1) (CBMAB-A9734-LY)

The product is antibody recognizes UBE2Z. The antibody 4B1 immunoassay techniques such as: WB, ELISA.
See all UBE2Z antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4B1
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
UBE2Z (NP_075567, 136 a.a. ~ 225 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
ubiquitin-conjugating enzyme E2Z
Introduction
Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE2Z is an E2 enzyme (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM
Entrez Gene ID
65264
UniProt ID
Q9H832
Alternative Names
FLJ13855; HOYS7; USE1
Function
Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).
Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process negative regulation of apoptotic process Source:GO_Central1 Publication
Biological Process positive regulation of apoptotic process Source:UniProtKB1 Publication
Biological Process ubiquitin-dependent protein catabolic process Source:Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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