UCKL1
The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Full Name
uridine-cytidine kinase 1-like 1
Function
May contribute to UTP accumulation needed for blast transformation and proliferation.
Biological Process
Biological Process CTP salvage Source:UniProtKB-UniPathway
Biological Process phosphorylation Source:UniProtKB-KW
Biological Process pyrimidine nucleoside salvage Source:Reactome
Biological Process UMP salvage Source:UniProtKB-UniPathway
Biological Process phosphorylation Source:UniProtKB-KW
Biological Process pyrimidine nucleoside salvage Source:Reactome
Biological Process UMP salvage Source:UniProtKB-UniPathway
Cellular Location
Cytoplasm
Nucleus
EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.
Nucleus
EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.
PTM
Ubiquitinated by RNF19B; which induces proteasomal degradation.
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Anti-UCKL1 antibodies
+ Filters

Target: UCKL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 8D4
Application*: E, IC, IF, WB
Target: UCKL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: CBCNC-731
Application*: WB
Target: UCKL1
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: B-11
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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