Mouse Anti-UCKL1 Recombinant Antibody (B-11) (CBMAB-C4486-CN)

Name: Mouse Anti-UCKL1 Recombinant Antibody (B-11)
SKU: CBMAB-C4486-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

B-11

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 31-142 mapping near the N-terminus of UCKL1 of human origin

Specificity

Human, Mouse, Rat

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

uridine-cytidine kinase 1-like 1

Introduction

The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Entrez Gene ID

Human	54963
Mouse	68556
Rat	499956

UniProt ID

Human	Q9NWZ5
Mouse	Q91YL3
Rat	D3ZYQ8

Alternative Names

Uridine-Cytidine Kinase 1 Like 1; EC 2.7.1.48; URKL1; Uridine-Cytidine Kinase 1-Like 1; Uridine-Cytidine Kinase-Like 1; Uridine Kinase-Like 1; UCK1-LIKE; UCK1L;

Function

May contribute to UTP accumulation needed for blast transformation and proliferation.

Biological Process

Biological Process CTP salvage Source:UniProtKB-UniPathway
Biological Process phosphorylation Source:UniProtKB-KW
Biological Process pyrimidine nucleoside salvage Source:Reactome
Biological Process UMP salvage Source:UniProtKB-UniPathway

Cellular Location

Cytoplasm
Nucleus
EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.

PTM

Ubiquitinated by RNF19B; which induces proteasomal degradation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-UCKL1 Recombinant Antibody (CBCNC-731) (CAT#: CBMAB-C4488-CN)

Mouse Anti-UCKL1 Monoclonal Antibody (8D4) (CAT#: CBMAB-1686-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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