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V. cholerae ctxA

Full Name

CtxA

Function

The A1 chain catalyzes the ADP-ribosylation of Gs alpha, a GTP-binding regulatory protein, to activate the adenylate cyclase. This leads to an overproduction of cAMP and eventually to a hypersecretion of chloride and bicarbonate followed by water, resulting in the characteristic cholera stool. The A2 chain tethers A1 to the pentameric ring.

Biological Process

Biological Process localization Source:DisProt1 Publication
Biological Process positive regulation of tyrosine phosphorylation of STAT protein Source:CACAO1 Publication

Cellular Location

catalytic complex
extracellular space
periplasmic space

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Anti-V. cholerae ctxA antibodies

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Mouse Anti-V. cholerae ctxA Recombinant Antibody (CBMC-C1063) (CBMAB-V208-0577-CQ)

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Target: V. cholerae ctxA

Host: Mouse

Antibody Isotype: IgM

Specificity: V. cholerae

Clone: CBMC-C1063

Application*: E

Mouse Anti-V. cholerae ctxA Recombinant Antibody (CBMC-C1108) (CBMAB-V208-0659-CQ)

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Target: V. cholerae ctxA

Host: Mouse

Antibody Isotype: IgM

Specificity: V. cholerae

Clone: CBMC-C1108

Application*: E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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