Mouse Anti-V. cholerae ctxA Recombinant Antibody (CBMC-C1063) (CBMAB-V208-0577-CQ)

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Basic Information

Host Animal
Mouse
Clone
CBMC-C1063
Application
ELISA
Immunogen
Vibrio cholerae extract
Specificity
V. cholerae
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
5.0 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
CtxA
Entrez Gene ID
UniProt ID
Alternative Names
ctxA; CtxA
Function
The A1 chain catalyzes the ADP-ribosylation of Gs alpha, a GTP-binding regulatory protein, to activate the adenylate cyclase. This leads to an overproduction of cAMP and eventually to a hypersecretion of chloride and bicarbonate followed by water, resulting in the characteristic cholera stool. The A2 chain tethers A1 to the pentameric ring.
Biological Process
Biological Process localization Source:DisProt1 Publication
Biological Process positive regulation of tyrosine phosphorylation of STAT protein Source:CACAO1 Publication
Cellular Location
catalytic complex
extracellular space
periplasmic space
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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