ZFAND5

Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Full Name
zinc finger, AN1-type domain 5
Function
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Biological Process
Biological Process face development Source:Ensembl
Biological Process fibroblast migration Source:Ensembl
Biological Process in utero embryonic development Source:Ensembl
Biological Process platelet-derived growth factor receptor signaling pathway Source:Ensembl
Biological Process respiratory system process Source:Ensembl
Biological Process skeletal system morphogenesis Source:Ensembl
Biological Process smooth muscle tissue development Source:Ensembl
Biological Process vasculature development Source:Ensembl
Cellular Location
Cytoplasm
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Anti-ZFAND5 antibodies

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Mouse Anti-ZFAND5 Recombinant Antibody (2F4) (CBMAB-Z0195-WJ)

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Target: ZFAND5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2F4
Application*: WB
Datasheet SDS

Mouse Anti-ZFAND5 Recombinant Antibody (9F2) (CBMAB-Z0194-WJ)

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Target: ZFAND5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9F2
Application*: P, WB
Datasheet SDS

Mouse Anti-ZFAND5 Recombinant Antibody (5B8) (CBMAB-Z0193-WJ)

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Target: ZFAND5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5B8
Application*: WB
Datasheet SDS

Mouse Anti-ZFAND5 Recombinant Antibody (5A9) (CBMAB-Z0192-WJ)

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Target: ZFAND5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5A9
Application*: WB
Datasheet SDS

Mouse Anti-ZFAND5 Recombinant Antibody (1D8) (CBMAB-Z0191-WJ)

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Target: ZFAND5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D8
Application*: P, WB
Datasheet SDS

Mouse Anti-ZFAND5 Recombinant Antibody (5H8) (CBMAB-Z0190-WJ)

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Target: ZFAND5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5H8
Application*: P, WB
Datasheet SDS

Mouse Anti-ZFAND5 Recombinant Antibody (2A2) (CBMAB-Z0189-WJ)

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Target: ZFAND5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2A2
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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