Mouse Anti-ZFAND5 Recombinant Antibody (9F2) (CBMAB-Z0194-WJ)

Name: Mouse Anti-ZFAND5 Recombinant Antibody (9F2)
SKU: CBMAB-Z0194-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

9F2

Application

IHC-P, WB

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/mL

More Infomation

Target

Full Name

zinc finger, AN1-type domain 5

Introduction

ZFAND5 (Zinc Finger AN1-Type Containing 5) is a Protein Coding gene. Among its related pathways are FoxO family signaling. An important paralog of this gene is ZFAND6.

Entrez Gene ID

7763

UniProt ID

O76080

Alternative Names

ZA20D2; ZNF216; ZFAND5A

Function

Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Biological Process

Biological Process face development Source:Ensembl
Biological Process fibroblast migration Source:Ensembl
Biological Process in utero embryonic development Source:Ensembl
Biological Process platelet-derived growth factor receptor signaling pathway Source:Ensembl
Biological Process respiratory system process Source:Ensembl
Biological Process skeletal system morphogenesis Source:Ensembl
Biological Process smooth muscle tissue development Source:Ensembl
Biological Process vasculature development Source:Ensembl

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-ZFAND5 Recombinant Antibody (2A2) (CAT#: CBMAB-Z0189-WJ)

Mouse Anti-ZFAND5 Recombinant Antibody (5A9) (CAT#: CBMAB-Z0192-WJ)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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