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Mouse Anti-FARP1 Recombinant Antibody (2D4) (CBMAB-A2835-LY)

The product is antibody recognizes FARP1. The antibody 2D4 immunoassay techniques such as: WB, ELISA.
See all FARP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2D4
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
FARP1 (NP_005757.1, 471 a.a. ~ 549 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
Introduction
This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain. It is believed to be a member of the band 4.1 superfamily whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Entrez Gene ID
UniProt ID
Alternative Names
CDEP; MGC87400; PLEKHC2
Research Area
Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity).
Biological Process
Dendrite morphogenesis Source: UniProtKB
Postsynaptic actin cytoskeleton organization Source: Ensembl
Regulation of presynapse assembly Source: Ensembl
Retrograde trans-synaptic signaling by trans-synaptic protein complex Source: Ensembl
Synapse assembly Source: UniProtKB
Cellular Location
Cytosol; Cell membrane; Synapse; Synaptosome; Filopodium; Dendrite; Dendritic spine. Recruited to the cell membrane via interaction with CADM1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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