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Mouse Anti-FARP1 Recombinant Antibody (CBXF-1725) (CBMAB-F3260-CQ)

This product is a mouse antibody that recognizes FARP1. The antibody CBXF-1725 can be used for immunoassay techniques such as: WB, IP, IF, IHC-P, ELISA.
See all FARP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXF-1725
Antibody Isotype
IgG
Application
WB, IP, IF, IHC-P, ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa471-549 from FARP1 (NP_005757) with GST tag
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
Introduction
This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
10160
UniProt ID
Q9Y4F1
Alternative Names
FERM, ARH/RhoGEF And Pleckstrin Domain Protein 1; FERM, RhoGEF (ARHGEF) And Pleckstrin Domain Protein 1 (Chondrocyte-Derived); Pleckstrin Homology Domain-Containing Family C Member 2; FERM, RhoGEF And Pleckstrin Domain-Containing Protein 1; Protein Phosphatase 1, Regulatory Subunit 75; Chondrocyte-Derived Ezrin-Like Protein; PH Domain-Containing Family C Member 2;
Research Area
Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity).
Biological Process
Dendrite morphogenesis Source: UniProtKB
Postsynaptic actin cytoskeleton organization Source: Ensembl
Regulation of presynapse assembly Source: Ensembl
Retrograde trans-synaptic signaling by trans-synaptic protein complex Source: Ensembl
Synapse assembly Source: UniProtKB
Cellular Location
Cytosol; Cell membrane; Synapse; Synaptosome; Filopodium; Dendrite; Dendritic spine. Recruited to the cell membrane via interaction with CADM1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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