Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-GUCY1A1 Recombinant Antibody (CBT4455) (V2LY-0625-LY919)


See all GUCY1A1 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4455
Antibody Isotype
IgG1
Application
WB, IHC, ICC, FC

Basic Information

Immunogen
Purified recombinant fragment of human GUCY1A3 (AA: 22-214) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
ICC1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Preservative
Sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Guanylate Cyclase 1 Soluble Subunit Alpha 1
Entrez Gene ID
2982
UniProt ID
Q02108
Biological Process
Blood circulation Source: ProtInc
cGMP biosynthetic process Source: UniProtKB
Nitric oxide mediated signal transduction Source: ProtInc
Positive regulation of nitric oxide mediated signal transduction Source: Ensembl
Regulation of blood pressure Source: Ensembl
Relaxation of vascular associated smooth muscle Source: Ensembl
Retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission Source: Ensembl
Cellular Location
Cytoplasm
Involvement in disease
Moyamoya disease 6 with or without achalasia (MYMY6):
A form of Moyamoya disease, a progressive cerebral angiopathy characterized by bilateral intracranial carotid artery stenosis and telangiectatic vessels in the region of the basal ganglia. The abnormal vessels resemble a 'puff of smoke' (moyamoya) on cerebral angiogram. Affected individuals can develop transient ischemic attacks and/or cerebral infarction, and rupture of the collateral vessels can cause intracranial hemorrhage. Hemiplegia of sudden onset and epileptic seizures constitute the prevailing presentation in childhood, while subarachnoid bleeding occurs more frequently in adults. MYMY6 is characterized by severe cerebral angiopathy and onset of severe achalasia in infancy or early childhood.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GUCY1A1 Recombinant Antibody (CBT4455)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry