A4GNT

This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. [provided by RefSeq, Jul 2008]

Full Name

Alpha-1,4-N-Acetylglucosaminyltransferase

Function

Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity).

Biological Process

Carbohydrate metabolic process
Glycoprotein biosynthetic process
Negative regulation of epithelial cell proliferation
O-glycan processing
Protein O-linked glycosylation

Cellular Location

Golgi apparatus membrane; Membrane protein

Topology

Cytoplasmic: 1-4 aa
Helical: 5-25 aa
Lumenal: 26-340 aa

Anti-A4GNT antibodies

Mouse Anti-A4GNT Recombinant Antibody (V2-178845) (CBMAB-A0061-YC)

Datasheet

SDS

Target: A4GNT

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-178845

Application*: WB

Mouse Anti-A4GNT Recombinant Antibody (V2-178846) (CBMAB-A0062-YC)

Datasheet

SDS

Target: A4GNT

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: V2-178846

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)