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A4GNT

This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. [provided by RefSeq, Jul 2008]

Full Name

Alpha-1,4-N-Acetylglucosaminyltransferase

Function

Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity).

Biological Process

Carbohydrate metabolic process
Glycoprotein biosynthetic process
Negative regulation of epithelial cell proliferation
O-glycan processing
Protein O-linked glycosylation

Cellular Location

Golgi apparatus membrane; Membrane protein

Topology

Cytoplasmic: 1-4 aa
Helical: 5-25 aa
Lumenal: 26-340 aa

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Anti-A4GNT antibodies

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Mouse Anti-A4GNT Recombinant Antibody (V2-178846) (CBMAB-A0062-YC)

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Target: A4GNT

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: V2-178846

Application*: WB

Mouse Anti-A4GNT Recombinant Antibody (V2-178845) (CBMAB-A0061-YC)

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Target: A4GNT

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: V2-178845

Application*: WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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