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Mouse Anti-A4GNT Recombinant Antibody (V2-178846) (CBMAB-A0062-YC)

Provided herein is a Mouse monoclonal antibody against Human Alpha-1,4-N-Acetylglucosaminyltransferase. The antibody can be used for immunoassay techniques, such as WB.
See all A4GNT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-178846
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 121-340 of human A4GNT produced in E.coli.
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Buffer
PBS, pH 7.3, 8% trehalose
Preservative
None
Concentration
1 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 121-340

Target

Full Name
Alpha-1,4-N-Acetylglucosaminyltransferase
Introduction
A4GNT is a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi appar
Entrez Gene ID
UniProt ID
Alternative Names
Alpha-1,4-N-Acetylglucosaminyltransferase; Alpha4GnT; EC 2.4.1.-;
Function
Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity).
Biological Process
Carbohydrate metabolic process
Glycoprotein biosynthetic process
Negative regulation of epithelial cell proliferation
O-glycan processing
Protein O-linked glycosylation
Cellular Location
Golgi apparatus membrane; Membrane protein
Topology
Cytoplasmic: 1-4 aa
Helical: 5-25 aa
Lumenal: 26-340 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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