AGPAT5

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. A pseudogene of this gene is present on the Y chromosome. [provided by RefSeq, Aug 2014]
Full Name
1-Acylglycerol-3-Phosphate O-Acyltransferase 5
Function
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable.
Biological Process
Acylglycerol metabolic process
CDP-diacylglycerol biosynthetic process
Hematopoietic progenitor cell differentiation
Phosphatidic acid biosynthetic process
Phospholipid biosynthetic process
Cellular Location
Endoplasmic reticulum membrane; Nucleus envelope; Mitochondrion
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Anti-AGPAT5 antibodies

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Target: AGPAT5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-180187
Application*: WB
Target: AGPAT5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-180186
Application*: IF, P, WB
Target: AGPAT5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-180185
Application*: P, WB
Target: AGPAT5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-180184
Application*: IH, WB
Target: AGPAT5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: V2-180183
Application*: F, P, WB
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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