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AGPAT5

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. A pseudogene of this gene is present on the Y chromosome. [provided by RefSeq, Aug 2014]

Full Name

1-Acylglycerol-3-Phosphate O-Acyltransferase 5

Function

Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable.

Biological Process

Acylglycerol metabolic process
CDP-diacylglycerol biosynthetic process
Hematopoietic progenitor cell differentiation
Phosphatidic acid biosynthetic process
Phospholipid biosynthetic process

Cellular Location

Endoplasmic reticulum membrane; Nucleus envelope; Mitochondrion

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Anti-AGPAT5 antibodies

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Mouse Anti-AGPAT5 Recombinant Antibody (V2-180187) (CBMAB-A1608-YC)

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Target: AGPAT5

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: V2-180187

Application*: WB

Mouse Anti-AGPAT5 Recombinant Antibody (V2-180186) (CBMAB-A1607-YC)

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Target: AGPAT5

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: V2-180186

Application*: IF, P, WB

Mouse Anti-AGPAT5 Recombinant Antibody (V2-180185) (CBMAB-A1606-YC)

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Target: AGPAT5

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: V2-180185

Application*: P, WB

Mouse Anti-AGPAT5 Recombinant Antibody (V2-180184) (CBMAB-A1605-YC)

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Target: AGPAT5

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: V2-180184

Application*: IH, WB

Mouse Anti-AGPAT5 Recombinant Antibody (V2-180183) (CBMAB-A1604-YC)

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Target: AGPAT5

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: V2-180183

Application*: F, P, WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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