AKAP4

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]
Full Name
A kinase (PRKA) anchor protein 4
Function
Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
Biological Process
Establishment of protein localization Source: Ensembl
Flagellated sperm motility Source: UniProtKB
Motile cilium assembly Source: Ensembl
Protein localization Source: GO_Central
Signal transduction Source: ProtInc
Single fertilization Source: ProtInc
Transmembrane receptor protein serine/threonine kinase signaling pathway Source: Ensembl
Cellular Location
Flagellum. Localizes to the principle piece of the sperm flagellum.
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Anti-AKAP4 antibodies

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Mouse Anti-AKAP4 Recombinant Antibody (V2-611075) (CBMAB-A0228-LY)

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Target: AKAP4
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: V2-611075
Application*: WB, E
Datasheet SDS

Mouse Anti-AKAP4 Recombinant Antibody (V2-611074) (CBMAB-A0227-LY)

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Target: AKAP4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-611074
Application*: WB, E, ICC/IF, IHC, P
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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