AKAP4

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

A kinase (PRKA) anchor protein 4

Major structural component of sperm fibrous sheath. Plays a role in sperm motility.

Establishment of protein localization Source: Ensembl
Flagellated sperm motility Source: UniProtKB
Motile cilium assembly Source: Ensembl
Protein localization Source: GO_Central
Signal transduction Source: ProtInc
Single fertilization Source: ProtInc
Transmembrane receptor protein serine/threonine kinase signaling pathway Source: Ensembl

Flagellum. Localizes to the principle piece of the sperm flagellum.